Ménétrier’s diseaseA condition characterised by enlarged rugal folds of the stomach, late development of parietal cell autoantibodies and gastric atrophy.
Decreased acid secretion, protein loss in the stomach, oedema, weight loss, abdominal pain, nausea and hypertrophic hypersecretory gastropathy; male:female ratio, 3:1; age 30–60.
May respond to cetuximab, anticholinergics, cimetidine, vagotomy and pyloroplasty.
An uncommon disorder marked by protein loss from the upper gastrointestinal tract and enlarged gastric rugal folds.
See also: gastropathy