hypersegmented neutrophil


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hy·per·seg·ment·ed neu·tro·phil

an aged and degenerated neutrophil in which there may be 6-10 lobes in the nucleus.

neutrophil

1. one of the three granular leukocytes having a nucleus with three to five lobes connected by threads of chromatin, and cytoplasm containing lysosomes that stain characteristically and enable neutrophils to be distinguished from basophils and eosinophils; called also a granulocyte or polymorphonuclear leukocyte. See also heterophil (1).
2. any cell, structure or histological element readily stainable with neutral dyes.

band neutrophil
see stab neutrophil (below).
neutrophil chemotactic factor
hypersegmented neutrophil
increased number of nuclear lobes; seen in hyperadrenocorticism or during treatment with corticosteroids, and in blood that has been in transit for long periods.
hyposegmented neutrophil
a lack of nuclear lobes; may occur in chronic infections and is a feature of pelger-huet anomaly.
neutrophil:lymphocyte ratio
correlates directly with the magnitude of the total leukocyte count in response to disease in domestic animals; it varies from 0.5 in cattle to 3.5 in dogs.
stab neutrophil
a neutrophilic leukocyte whose nucleus is not divided into segments.
toxic neutrophil
one with blue-black or large reddish cytoplasmic granules and diffuse cytoplasmic basophilia and vacuolation; caused by disruption of maturation.