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The influx of eosinophils, macrophages, and lymphocytes into the airways was also markedly suppressed; however, these mice remained hyperresponsive to metacholine. An inadequately anesthetized patient is apt to be uncomfortable, anxious, and hyperresponsive and therefore unlikely to tolerate the procedure. But while the levels of ACTH didn't jump, the adrenals were hyperresponsive, producing large amounts of cortisol--as they would if they were constantly stimulated by ACTH. |
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