hyperprolactinemia


Also found in: Dictionary, Wikipedia.

hyperprolactinemia

 [hi″per-pro-lak″tin-e´me-ah]
increased levels of prolactin in the blood; in women it is associated with amenorrhea and often galactorrhea, and it has been reported to cause impotence in men.

hy·per·pro·lac·ti·ne·mi·a

(hī'pĕr-prō'lak-ti-nē'mē-ă),
Elevated levels of prolactin in the blood, which is a normal physiologic reaction during lactation and pregnancy, but pathologic otherwise; prolactin may also be elevated in cases of certain pituitary tumors, and amenorrhea is often present.

hyperprolactinemia

/hy·per·pro·lac·tin·emia/ (-pro-lak″tĭ-ne´me-ah) increased levels of prolactin in the blood, often associated with pituitary adenoma.hyperprolactine´mic

hyperprolactinemia

(hī′pər-prō-lăk′tə-nē′mē-ə)
n.
An elevated level of prolactin in the blood.

hyperprolactinemia

[-prōlak′tinē′mē·ə]
Etymology: Gk, hyper + L, pro, before, lac, milk; Gk, haima, blood
an excessive amount of prolactin in the blood, usually caused by a pituitary adenoma but sometimes caused by endocrine side effects related to certain antipsychotic medications. In women it is usually associated with galactorrhea and secondary amenorrhea; in men it may be a factor in gynecomastia, decreased libido, and impotence. Also spelled hyperprolactinaemia.

hy·per·pro·lac·ti·ne·mi·a

(hī'pĕr-prō-lak'ti-nē'mē-ă)
Elevated levels of prolactin in the blood; a normal physiologic reaction during lactation, but pathologic otherwise; often due to physical or emotional stress or rapid weight loss, sometimes to pituitary adenoma; amenorrhea is usually present.
Synonym(s): hyperprolactinaemia.

hyperprolactinemia

increased levels of prolactin in the blood; occurs in severe hypothyroidism, caused by excessive thyrotropin-releasing hormone. Galactorrhea and anestrus results.
References in periodicals archive ?
The consensus report includes recommendations for the detection and management of the full range of manifestations of iatrogenic hyperprolactinemia, including osteoporosis and hip fracture, hypogonadism, premature menopause, cardiovascular disease, breast and endometrial cancer, and immunologic disorders.
Studies in nonhuman primates and laboratory animals have confirmed an alcohol-induced hyperprolactinemia.
Gestational gigantomastia is a complication whose etiology and pathogenesis have yet to be fully clarified; however, various theories including endocrine imbalance, hyperprolactinemia and end organ hypersensitivity have been suggested by different researchers (3, 4).
Longstanding hyperprolactinemia associated with systemic lupus erythematosus possible hormonal stimulation of an autoimmune disease.
Hyperprolactinemia in hypothyroidism: clinical significance and impact of TSH normalization.
Approach to the patient with persistent hyperprolactinemia and negative sellar imaging.
Clinical trials have demonstrated the beneficial effects of some drugs like Peony-Glycirrhiza Decoction (PGD) in alleviating antipsychotic induced hyperprolactinemia in schizophrenic patients [6], AS PGD suppress prolactin levels in MMQ cells, in volving modulating the expression of D2 receptor (Dr D2) and dopamine transporter (DAT).
Therefore, adding aripiprazole to existing antipsychotic regimens is reasonable for patients with drug-induced symptomatic hyperprolactinemia or metabolic effects and who cannot be easily switched to another antipsychotic.
2A] antagonism promote sexuality Lack of hyperprolactinemia in addition to these receptor effects may be the cause of spontaneous ejaculations in our patient, although further research is needed to clearly explain the sexual effects of aripiprazole.
Hyperprolactinemia may cause loss of libido and low levels of serum testosterone.