In the hippocampus and the prefrontal cortex, for example, this potentiation and subsequent binding of GABA hyperpolarizes
the cell making the release of acetylcholine less likely.
The PIA sends projections to NGC (74), NMC (71,75) and NPM (76) of the medullary region, which in turn project to the spinal cord (72,75,77) to hyperpolarize
motoneurons to control the spinal circuits for inducing atonia during REM sleep (78,79).
Efflux of potassium through an activated channel hyperpolarizes
the excitable membrane and provides an effective means of suppressing neuronal firing.
During an action potential, the plasma membrane depolarizes to approximately 0 V and the vacuolar membrane hyperpolarizes
to approximately -0.
2]]-methionine-enkephalinamide (DALA), which hyperpolarizes
interneurons, suggesting that the inhibition of the late IPSP by NE may result from the [[alpha].