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hyperpolarized helium

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hyperpolarized helium
[-pō′lərīzd]
a gas used in magnetic resonance imaging studies of respiratory disorders to produce images of the air spaces in the lungs.


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The researchers developed a method of using hyperpolarized helium gas to observe the lung as gas flows in and out, providing them high-resolution images of human ventilation.
Evidence for severe heterogeneity of regional ventilation in patients with asthma has come from measurements with external scintillation counters (1,2), single-photon emission computed tomography (CT) of Technegas (3), nuclear magnetic resonance imaging after a single-breath inhalation of hyperpolarized helium (4), and high-resolution CT (5-10).
With selected bronchi occluded, collateral resistance may be inferred from the distribution of inhaled gas during a single breath using xenon and ventilation scintigraphy or hyperpolarized helium and magnetic resonance imaging (10).
 
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