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hyperpolarization
(redirected from hyperpolarized)

   Also found in: Dictionary/thesaurus, Wikipedia 0.01 sec.
hyperpolarization /hy·per·po·lar·iza·tion/ (hi″per-po″ler-ĭ-za´shun) any increase in the amount of electrical charge separated by the cell membrane, and hence in the strength of the transmembrane potential.
hyperpolarization
an increase in the amount of electrical charge on either side of a cell membrane so that there is an increase in the electric potential across the membrane.

hyperpolarization
A change in the value of the resting membrane potential towards a more negative value. The inside of the cell becomes more negative than the outside. Hyperpolarization is inhibitory because the membrane potential moves away from the neuron's threshold at which an action potential could occur. Example: the retinal photoreceptor potentials when stimulated by light. See depolarization; receptor potential; resting membrane potential; synapse.


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In addition, they slow the rate of VSSC inactivation (or closing) and shift to more hyperpolarized potentials the membrane potential at which VSSCs activate (or open) (for review, see Narahashi 1996).
70), Pines and his colleagues hyperpolarized the xenon nuclei, aligning their spins and thereby enhancing their MRI signal.
Using the bidomain model and fluorescent dye methods, the Vanderbilt team predicted that there would be an excessively positive, or hyperpolarized, area on either side of the virtual cathode.
 
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