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hyperostosis |
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hyperostosis /hy·per·os·to·sis/ (-os-to´sis) hypertrophy of bone.hyperostot´ic hyperostosis cortica´lis defor´mans juveni´lis an inherited disorder of limb fractures and bowing, thickening of skull bones, osteoporosis, and elevated levels of serum alkaline phosphatase and urinary hydroxyproline. hyperostosis cortica´lis generalisa´ta a hereditary disorder beginning during puberty, marked chiefly by osteosclerosis of the skull, mandible, clavicles, ribs, and diaphyses of long bones, associated with elevated blood alkaline phosphatase. hyperostosis cra´nii hyperostosis involving the cranial bones. hyperostosis fronta´lis inter´na thickening of the inner table of the frontal bone, which may be associated with hypertrichosis and obesity, most commonly affecting women near menopause. infantile cortical hyperostosis a disease of young infants, with soft tissue swelling over affected bones, fever, irritability, and periods of remission and exacerbation.
hyperostosis (hī´p n 1. an excessive growth of bone, as in infantile cortical hyperostosis. n 2. a hypertrophy of bone. See also exostosis. hyperostosis, infantile cortical (Caffey's disease, Smyth's syndrome), n a disease of infants; of unknown cause and characterized by tender, soft tissue swelling that is followed by hyperostosis of the cortex of the underlying bone. The mandible, clavicle, and ulna are most frequently affected. hyperostosis excessive growth of bony tissue. craniomandibular hyperostosis see craniomandibular osteopathy. diffuse idiopathic skeletal hyperostosis (DISH) occurs in dogs and pigs; cause unknown, possibly familial in pigs; extensive bone deposition around joints but articular surfaces not affected. facial hyperostosis in hyperparathyroidism resorption of cancellous bone, particularly maxillae and mandibles, and the formation of poorly mineralized osteoid and excessive fibro-osseous tissue cause deformities of the face and head that are clinically obvious and may prevent closure of the mouth. Occurs in primary and secondary hyperparathyroidism. inherited congenital hyperostosis see juvenile hyperostosis (below). juvenile hyperostosis a congenital defect of pigs. The legs of affected newborn pigs are swollen below the elbow. The piglets have difficulty standing and moving around. The bone is thick and the periosteum rough and there is extensive edema. Called also thick forelegs, inherited congenital hyperostosis. |
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