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hypermotility

   Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia, Hutchinson 0.01 sec.
hypermotility /hy·per·mo·til·i·ty/ (hi″per-mo-til´ĭ-te) abnormally increased motility, as of the gastrointestinal tract.
hypermotility
[-motil′itē]
an excessive movement of the involuntary muscles, particularly in the GI tract. Compare hypomotility.

hypermotility
excessive or abnormally increased motility.

gut hypermotility
decreased transit time for the entire alimentary tract.
intestinal hypermotility
is characterized by increase in gut sounds, spasms of pain, e.g. in spasmodic colic in horses and, in some cases, diarrhea.


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In addition, the Company's pipeline includes TZP-102 for chronic gastroparesis, TZP-201 for intestinal hypermotility, and TZP-301 for obesity.
Tranzyme is developing first-in-class, mechanism-based therapeutics for post-operative ileus (POI), gastroparesis, obesity, diabetes and intestinal hypermotility.
These data suggest that motilin antagonism has therapeutic potential in the treatment of GI disorders characterized by hypermotility or absorptive disorders in the gut.
 
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