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hyperkeratosis |
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hyperkeratosis /hy·per·ker·a·to·sis/ (-ker?ah-to´sis) 1. hypertrophy of the stratum corneum of the skin, or any disease so characterized. 2. hypertrophy of the cornea. epidermolytic hyperkeratosis a hereditary disease, with hyperkeratosis, blisters, and erythema; at birth the skin is entirely covered with thick, horny, armorlike plates that are soon shed, leaving a raw surface on which scales then reform. hyperkeratosis follicula´ris in cu´tem pe´netrans Kyrle's disease.
hyperkeratosis (hī´purker´ n an excessive formation of keratin (e.g., as seen in leukoplakia). hyperkeratosis, benign, n a nonmalignant form of a thickening condition that affects the keratin layer of the oral mucosa; generally appears as a white lesion. hyperkeratosis 1. hypertrophy of the horny layer (stratum corneum) of the skin, or any disease characterized by it; the hyperkeratoses may have distinctive formats, e.g. annular (ring formations), basket-weave, compact, laminated. 2. hypertrophy of the cornea. bovine hyperkeratosis chlorinated naphthalene poisoning. digital hyperkeratosis increased thickness of the keratinized epidermis of footpads in dogs and rarely cats. May be in response to trauma or associated with distemper (hardpad disease), or pemphigus foliaceus. epidermolytic hyperkeratosis a form of ichthyosis in humans which is inherited as an autosomal dominant trait; there is severe degeneration of the granular layer of the epidermis. juvenile hyperkeratosis a crusting dermatosis over bony prominences, face and chin of young dogs. See zinc-responsive dermatosis. nasal hyperkeratosis an abnormal thickening, sometimes with fissures, of the planum nasale of dogs. May occur in association with digital hyperkeratosis (see above) as a feature of distemper (hardpad disease). Also seen in pemphigus foliaceus and discoid lupus erythematosus. nasodigital hyperkeratosis see nasal hyperkeratosis, digital hyperkeratosis (above). orthokeratotic hyperkeratosis hyperkeratosis with non-nucleated cells present. parakeratotic hyperkeratosis hyperkeratosis with nucleated cells present; called also parakeratosis. |
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