hyperkeratosis


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hyperkeratosis

 [hi″per-ker″ah-to´sis]
1. hypertrophy of the horny layer of the skin, or any disease characterized by it.
2. hypertrophy of the cornea. adj., adj hyperkeratot´ic.
epidermolytic hyperkeratosis a hereditary autosomal dominant form of ichthyosis, present at birth. Characteristics include generalized redness of the skin and severe hyperkeratosis with small, hard wartlike scales over the entire body, accentuated in areas that flex or bend and sometimes involving the palms and soles. In infancy and childhood, there are recurrent bullae, most often on the lower limbs.
follicular hyperkeratosis a skin condition characterized by excessive development of keratin in hair follicles, resulting in rough, cone-shaped, elevated papules, the openings of which are often closed with a white plug of encrusted sebum. Deficiencies of vitamins A and E, B complex vitamins, and essential fatty acids have all been implicated in the etiology. Called also phrynoderma.
hyperkeratosis lenticula´ris per´stans an autosomal dominant skin disorder, usually occurring in the third or fourth decade of life, characterized by pink, red, or yellow to brown scaly papules on the lower leg and back of the foot, and sometimes on the trunk, thigh, arm, back and palm of the hand, or sole of the foot.

hy·per·ker·a·to·sis

(hī'pĕr-ker'ă-tō'sis),
Thickening of the horny layer of the epidermis or mucous membrane.
See also: keratoderma, keratosis.
Synonym(s): hyperkeratinization

hyperkeratosis

/hy·per·ker·a·to·sis/ (-ker″ah-to´sis)
1. hypertrophy of the stratum corneum of the skin, or any disease so characterized.
2. hypertrophy of the cornea.

epidermolytic hyperkeratosis  a hereditary disease, with hyperkeratosis, blisters, and erythema; at birth the skin is entirely covered with thick, horny, armorlike plates that are soon shed, leaving a raw surface on which scales then reform.
hyperkeratosis follicula´ris in cu´tem pe´netrans  Kyrle's disease.

hyperkeratosis

(hī′pər-kĕr′ə-tō′sĭs)
n. pl. hyperkerato·ses (-sēz)
Hypertrophy of the cornea or the horny layer of the skin.

hy′per·ker′a·tot′ic (-tŏt′ĭk) adj.

hyperkeratosis

[-ker′ətō′sis]
Etymology: Gk, hyper + keras, horn, osis, condition
overgrowth of the cornified epithelial layer of the skin. See also callus, corn. hyperkeratotic, adj.

hyperkeratosis

Dermatology An ↑ in superficial keratinized layers of certain epithelia, skin, and uterine cervix; hyperkeratosis usually represents a reaction to irritation, and generally overlies benign epithelium

hy·per·ker·a·to·sis

(hī'pĕr-ker'ă-tō'sis)
Thickening of the horny layer of the epidermis or mucous membrane.
See also: keratoderma, keratosis
Synonym(s): hyperkeratinization.

hyperkeratosis

Undue thickening of the outer layer of the skin so that a dense horny layer, such as a corn or callosity, results. This is a normal and essentially protective response to local pressure. Hyperkeratosis may also occur as an inherited disorder of the palms and the soles, or as ICHTHYOSIS.

hy·per·ker·a·to·sis

(hī'pĕr-ker'ă-tō'sis)
Thickening of the horny layer of the epidermis or mucous membrane.

hyperkeratosis

1. hypertrophy of the horny layer (stratum corneum) of the skin, or any disease characterized by it; the hyperkeratoses may have distinctive formats, e.g. annular (ring formations), basket-weave, compact, laminated.
2. hypertrophy of the cornea.

bovine hyperkeratosis
chlorinated naphthalene poisoning.
digital hyperkeratosis
increased thickness of the keratinized epidermis of footpads in dogs and rarely cats. May be in response to trauma or associated with distemper (hardpad disease), or pemphigus foliaceus.
epidermolytic hyperkeratosis
a form of ichthyosis in humans which is inherited as an autosomal dominant trait; there is severe degeneration of the granular layer of the epidermis.
juvenile hyperkeratosis
a crusting dermatosis over bony prominences, face and chin of young dogs. See zinc-responsive dermatosis.
nasal hyperkeratosis
an abnormal thickening, sometimes with fissures, of the planum nasale of dogs. May occur in association with digital hyperkeratosis (see above) as a feature of distemper (hardpad disease). Also seen in pemphigus foliaceus and discoid lupus erythematosus.
Enlarge picture
Nasal hyperkeratosis. By permission from Kummel BA, Color Atlas of Small Animal Dermatology, Mosby, 1989
nasodigital hyperkeratosis
see nasal hyperkeratosis, digital hyperkeratosis (above).
orthokeratotic hyperkeratosis
hyperkeratosis with non-nucleated cells present.
parakeratotic hyperkeratosis
hyperkeratosis with nucleated cells present; called also parakeratosis.
References in periodicals archive ?
In addition, an increase in OGG1 expression was associated with an increased risk of skin hyperkeratosis in males induced by chronic exposure to As.
Only charts of patients whose Papanicolaou smears showed hyperkeratosis without other pathological diagnoses were selected for review.
Haematoxylin and Eosin stained Section of Lichen amyloidosis at 40x Magnification showing Hyperkeratosis, Papillomatosis, Acanthosis and Dermal Infiltrate along with Amyloid
The syndrome of palmar plantar hyperkeratosis and premature periodontal destruction of the teeth.
So, from this study we have found that squamous metaplasia, hyperkeratosis, and parakeratosis were statistically significant findings in patients with uterine prolapse when compared with patients without prolapse.
Records of milk yield, mastitis occurrence and hyperkeratosis of 453 Holstein cows (with 1812 teats) from a large herd with calving dates from December 2012 to December 2014 in Qazvin province of Iran were used in this study.
Due to the fact that cutaneous nodules, either ulcerated or not, and generalized footpad hyperkeratosis accompanied by depigmentation and erosion were the main constituents of the cutaneous disease in this dog and its many clinical similarities to canine leishmaniosis (Leishmania infantum/chagasi) [12, 20], made its exclusion with the aid of serology and cytology a diagnostic priority.
Hyperkeratosis may appear on the knees, hands, buttocks, elbows, and axillae.
There was information on identifying the signs that milking is not being carried out gently or effectively, with tell-tale signals including discoloured teats post-milking or teat-end hyperkeratosis.
Histologic evidence of hyperkeratosis on biopsy in the context of characteristic clinical signs confirms the diagnosis.
A skin biopsy taken from the arm showed epidermal hyperkeratosis, focal parakeratosis, exocytosis, diffuse lysis of the basal layer, band-like lymphocytic infiltration of the dermis, lymphocytic infiltrate around the hair follicle, and scattered melanin incontinence (Figure-2a).