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hyperinsulinism

   Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia 0.04 sec.
hyperinsulinism /hy·per·in·su·lin·ism/ (-in´sŭ-lin-izm″)
1. excessive secretion of insulin.

hy·per·in·su·lin·ism (hpr-ns-l-nzm)
n.
A condition marked by excessive secretion of insulin by the islets of Langerhans, resulting in hypoglycemia; the symptoms are similar to those of insulin shock, though more chronic in character.

hyperinsulinism
[-in′səliniz′əm]
Etymology: Gk, hyper + L, insula, island
an excessive amount of insulin in the body. It may be caused by administration of an insulin dose greater than required or the presence of an insulin-secreting tumor in the islets of Langerhans or insulin reference. If there is hypoglycemia, symptoms include hunger, shakiness, and diaphoresis. See also insulin shock.

hyperinsulinism
1. excessive secretion of insulin by the pancreas, resulting in hypoglycemia. See also insulinoma.
2. insulin shock from overdosage of insulin.

Patient discussion about hyperinsulinism.

Q. My husband is diabetic and is living with insulin. He is again having nausea, heartburn, high bloating.. My husband is diabetic and is living with insulin injection. I am paralyzed in one leg and I am home bound. He is the sole earning person in our family to meet our financial needs. He has developed a high stress and depression due to his work which makes him to travel very frequently. He is holding a position in Sales Department. He was given antidepressants. They had helped him to reduce on his stress. But his stomach problems have increased after taking antidepressants. He is again having nausea, heartburn, high bloating and he even eats less as he feels himself full. This is giving stress to him and his depression is increasing again. What do we do? He is living a terrible life.

A. Stomach problem like Gastroparesis is associated with type 1 diabetes. His diabetes with high work related stress has increased his depression problem as well. Persons having antidepressants can have these symptoms of gastro paresis which gets doubled with diabetes. You must meet your doctor and proceed with the treatment. This can also happen due to poor sugar control. He can eat 6-7 meals per day instead of regular three meals this will be of good help.
http://www.youtube.com/watch?v=-5jcOo25ms0&eurl=http://www.imedix.com/health_community/v-5jcOo25ms0_tcoyd_diabetes_gastrointestinal_tract?q=gastro%20paresis%20with%&feature=player_embedded

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Persistent hyperinsulinism in infants or children is a complex disorder that requires prompt evaluation and treatment by a specialist.
Approximately 50% of insulin is normally cleared in its first pass through the liver; therefore, peripheral delivery causes significant peripheral hyperinsulinism and reduces the exposure of the liver to high insulin concentrations.
Other causes of postprandial hypoglycemia can include overactive islet cells, sometimes caused by excess numbers of cells, a tumor in the pancreas that produces too much insulin, or familial hyperinsulinism (hereditary production of too much insulin), which in severe cases can necessitate removal of the pancreas.
 
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