hyperinfection syndrome

hyperinfection syndrome

Disseminated parasitosis in immunosuppressed, malignant, or malnourished hosts, caused by autoinfection with Strongyloides stercoralis Clinical Abrupt onset of high fever, abdominal pain, bloating, intestinal ulcerations, gram-negative sepsis and shock; intense transpulmonary nematodal migration results in dyspnea, cough, hemoptysis Treatment Thiabendazole Prevention Wear shoes, boil water

Hyperinfection syndrome

A condition of massive infection in which threadworm larvae multiply rapidly and spread throughout the body. It is usually associated with damage to the immune system, the use of steroid medications, or malnutrition.
Mentioned in: Threadworm Infection
References in periodicals archive ?
In immunocompromised patients, the endogenous autoinfection cycle may result in the overproduction and dissemination of larvae into intestinal and extraintestinal tissues, including the central nervous system, leading to the hyperinfection syndrome which can be lethal (5).
Although our patient exhibited poor general condition, he likely did not experience hyperinfection syndrome because he was not immunosuppressed, and he completely recovered after receiving standard ivermectin treatment.
Strongyloides hyperinfection syndrome in British veterans.
The most common nematodes to consider include Strongyloides stercoralis as part of a hyperinfection syndrome, Toxocara species or less commonly Baylisascaris species as agents of visceral larva migrans, or other nematode worms that may involve the CNS such as Angiostrongylus and Gnathostoma species.
2), (3) During autoreinfection, the larvae disseminates into the intestinal track, pulmonary tissue, and skin, resulting in a hyperinfection syndrome with a fatality rate of 90%.
Intestional Strongyloidasis and hyperinfection syndrome.
In HIV-infected patients, the presence of peripheral eosinophilia should always raise the suspicion of the strongyloides hyperinfection syndrome.
Defective T -cell responses coupled with autoinfection cycles account for heavy worm burdens in some immunosuppressed individuals and lead to hyperinfection syndrome and disseminated strongyloidiasis.
Abstract: Strongyloides hyperinfection syndrome is one of several clinical manifestations of strongyloidiasis and has a mortality rate exceeding 85%.
Key Words: hyperinfection syndrome, Pneumocystis jiroveci, pneumonia, strongyloidiasis
2) There are two severe forms of strongyloidiasis: hyperinfection syndrome and disseminated strongyloidiasis.
Longworth DL, Weller PF: Hyperinfection syndrome with strongyloidiasis.