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hyperimmunoglobulin M syndrome

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hyperimmunoglobulin M syndrome
Hyper-IgM syndrome Immunology An X-R immunodeficiency Clinical Recurrent bacterial infections–eg, otitis media, pneumonia or opportunistic infections, recurrent neutropenia, lymphoid hyperplasia, neoplasia at an early age, and autoimmune phenomena Lab ↓/absent IgG, IgA, IgE; normal/↑ IgM, IgD


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CVID is partially a diagnosis of exclusion, in that other primary antibody deficiencies such as X-linked agammaglobulinemia and hyperimmunoglobulin M syndrome must not be present.
 
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