hypercalcitonism

hypercalcitonism

a state in which a high blood calcitonin level is maintained because of abnormalities in the secretion of calcitonin. May be caused by a chronic overfeeding of calcium or functional medullary (C cell) thyroid neoplasms. Leads to a persistent hypocalcemia, arrested bone resorption and osteosclerosis. See also c cell tumors.

nutritional secondary hypercalcitonism
caused in ruminants by a prolonged high-calcium diet, of three to five times the recommended intake, and results in a blocking of normal bone resorption and the development of osteopetrosis and ankylosing spondylosis.