hyperalgesia


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Related to hyperalgesia: Hyperpathia, Neuropathic pain

hyperalgesia

 [hi″per-al-je´ze-ah]
excessive sensitivity to pain. adj., adj hyperalge´sic.

hy·per·al·ge·si·a

(hī'pĕr-al-jē'zē-ă),
Excessive sensitivity and a raised threshold to painful stimuli.
[hyper- + G. algos, pain]

hyperalgesia

/hy·per·al·ge·sia/ (-al-je´ze-ah) abnormally increased pain sense.hyperalge´sic

hyperalgesia

(hī′pər-ăl-jē′zhə)
n.
Extreme sensitivity to pain.

hy′per·al·ge′sic (-zĭk) adj.

hy·per·al·ge·sia

(hī'pĕr-al-jē'zē-ă)
Extreme sensitivity to painful stimuli.
[hyper- + G. algos, pain]

hyperalgesia

increased sensitivity to pain; innocuous stimuli are perceived as pain; characteristic of neuropathic pain

hy·per·al·ge·sia

(hī'pĕr-al-jē'zē-ă)
Increased response to pain exceeding that normally elicited by such pain.
[hyper- + G. algos, pain]

hyperalgesia (hī´pəraljē´zēə),

n a greater-than-normal sensitivity to pain that may result from a painful stimulus or a lowered pain threshold.

hyperalgesia

a state of abnormally increased sensitivity to pain or nociceptive stimuli, as occurs under the influence of low doses of barbiturate anesthetic drugs.
References in periodicals archive ?
Thermal hyperalgesia were assessed with the paw withdrawal latency (PWL) to radiant heat according to the protocol of Hervera et al.
For instance, drugs for persistent pain are often tested solely for their ability to reduce hyperalgesia, and as a result, some of the drugs that are effective in the lab, fail in subsequent clinical trials.
Studies in the rat model confirm a switch to a G (i)-activated and PKC epsilon-dependent signaling pathway in primary mechanical hyperalgesia that is induced by stress or inflammation (17).
Sensory: evidence of hyperalgesia (to pinprick) and/or allodynia (to light touch and/or deep somatic pressure and/or joint movement)
Magnesium deficiency induces an hyperalgesia reversed by the NMDA receptor antagonist MK801.
The von Frey hair test, which resembles the Semmes-Weinstein test, was used for determining a mechanical hyperalgesia.
The release of prostaglandin also plays a role in migraines, sensitizing peripheral nociceptors to pain and mediating hyperalgesia, and prostaglandin is known to increase during migraine attacks.
NGF plays a critical role in hyperalgesia and allodynia as established in animal models.
HT-20 has been found to inhibit inflammatory swelling and hyperalgesia and to suppress pro-inflammatory cytokines in a rat inflammation model.
They suffer from localised symptoms such as constant burning, stabbing and shooting pain, allodynia and hyperalgesia.
The topics discussed cover the problems involved in providing basic cancer care in developing countries, psychosocial implications of the diagnosis and living with cancer, clinical problems associated with neuropathic pain, hyperalgesia and opioid rotation.
This increased sensitivity is clinically known as opioid-induced hyperalgesia (OIH).