hyperalgesia


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Related to hyperalgesia: Hyperpathia, Neuropathic pain

hyperalgesia

 [hi″per-al-je´ze-ah]
excessive sensitivity to pain. adj., adj hyperalge´sic.

hy·per·al·ge·si·a

(hī'pĕr-al-jē'zē-ă),
Excessive sensitivity and a raised threshold to painful stimuli.
[hyper- + G. algos, pain]

hyperalgesia

/hy·per·al·ge·sia/ (-al-je´ze-ah) abnormally increased pain sense.hyperalge´sic

hyperalgesia

(hī′pər-ăl-jē′zhə)
n.
Extreme sensitivity to pain.

hy′per·al·ge′sic (-zĭk) adj.

hy·per·al·ge·sia

(hī'pĕr-al-jē'zē-ă)
Extreme sensitivity to painful stimuli.
[hyper- + G. algos, pain]

hyperalgesia

increased sensitivity to pain; innocuous stimuli are perceived as pain; characteristic of neuropathic pain

hy·per·al·ge·sia

(hī'pĕr-al-jē'zē-ă)
Increased response to pain exceeding that normally elicited by such pain.
[hyper- + G. algos, pain]

hyperalgesia (hī´pəraljē´zēə),

n a greater-than-normal sensitivity to pain that may result from a painful stimulus or a lowered pain threshold.

hyperalgesia

a state of abnormally increased sensitivity to pain or nociceptive stimuli, as occurs under the influence of low doses of barbiturate anesthetic drugs.
References in periodicals archive ?
Intrathecal administration of the sFKN (14-17), but not full-length FKN (14) induces thermal hyperalgesia and mechanical allodynia, which is blocked by pretreatment with neutralizing antibody against CX3CR1 (15,16) or neutralized in CX3CR1 knockout mice (18).
As a result, hypersensitivity manifests as both hyperalgesia and allodynia occurs, for which standard analgesic treatments are unsuccessful.
All patients presented with a disturbance in pinprick sensation, temperature sensation, and/or allodynia or hyperalgesia, which was in accordance with the clinical manifestations of SFN.
17] Since TRPA1 and TRPV4 are the two key participants in mechanical hyperalgesia, together with their high co-expression and synergy effect with TRPV1, it is concluded that TRPA1 and TRPV4 mediated mechanical hyperalgesia is more critical in KOA pain.
2013) Morphine hyperalgesia gated through microglia-mediated disruption of neuronal Cl(-) homeostasis.
On physical evaluation, she presented pain provoked by typically nonpainful stimuli (allodynia) and hyperalgesia in the left thoracic region from the root of the fourth thoracic dermatome to the tenth thoracic dermatome.
The plantar incision produced a marked mechanical hyperalgesia in the injured paw at all of the time points measured in mice treated with vehicle, when compared with the baseline values (B).
Additionally, the report provides an overview of key players involved in therapeutic development for Hyperalgesia and features dormant and discontinued projects.
This decrease was accepted as a sign of the development of hyperalgesia in rats (p<0.
The experimental animals were subjected for various behavioral studies for assessment of hyperalgesia and allodynia carried out on the different day intervals of 0, 1, 7, 14 and 21 days.
February 18, 2016 -- Cleveland Clinic researchers have found evidence in an animal study that modulating neuro-inflammation with stem cell transplants may prove to be an effective strategy to treat both opioid tolerance (OT) and opioid-induced hyperalgesia (OIH).