hydroxysteroid


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hydroxysteroid

/hy·droxy·ste·roid/ (-ster´oid) a steroid carrying a hydroxyl group.
References in periodicals archive ?
As mentioned, both 5a-DHT metabolites, 3a-Adiol and 3[beta]-Adiol, are products of hydroxysteroid dehydrogenases.
Congenital adrenal hyperplasia secondary to 3-beta hydroxysteroid dehydrogenase deficiency
Environmental pollutants and hydroxysteroid dehydrogenases.
signal transducer and activator of transcription 1,91kDa (STAT1), guanylate binding protein 1, interferon-inducible (GBP1), and hydroxysteroid (17beta) dehydrogenase 1 (HSD17B1) in 10 additional plasma samples from third-trimester pregnant women, as well as keratin 18 (KRT18) and growth arrest and DNA-damage-inducible, gamma (GADD45G) in 10 plasma samples from another cohort of third-trimester pregnant women (see online Supplemental Fig.
Emodin, a natural product, selectively inhibits 11 beta- hydroxysteroid dehydrogenase type I and ameliorates metabolic disorder in diet - induced obese mice.
UM15-4 PGD - Hydroxysteroid Dehydrogenase 4 Deficiency, a rare hormone disorder
Elevated levels of free fatty acids, insulin and several adipokines, as observed in metabolic syndrome, induce hydroxysteroid dehydrogenase type 1 (11[beta]-HSD1) gene expression in the liver.
Pseudohyperaldosteronism can be caused by overconsumption of Glycyrrhiza glabra (licorice) because glycyrrhizin inhibits 11-beta hydroxysteroid dehydrogenase thus preventing Cortisol's inactivation to cortisone in the kidney and thereby potentiating the mineralocoricoid effect of endogenous Cortisol.
It was observed in vitro that Hg exposure significantly altered the androgen synthesis pathway by inhibiting hydroxysteroid sulphotransferase (HST) activity, thus reducing the conversion of dehydroepiandrosterone (DHEA) to dehydroepiandrosterone-sulphate (DHEAS) (21-24).
Splanchnic cortisol production occurs in humans: evidence for conversion of cortisone to cortisol via the 11-beta hydroxysteroid dehydrogenase (11 beta-hsd) type 1 pathway.
However, an enzyme called 11-[Beta] hydroxysteroid dehydrogenase type 2 is expressed in traditional aldo- sterone target tissues and vascular smooth muscle cells that convert cortisol to cortisone.
Placental 11-beta hydroxysteroid dehydrogenase methylation is associated with newborn growth and a measure of neurobehavioral outcome.