hydroxamic acids


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hy·drox·am·ic ac·ids

(hī'drok-sam'ik as'idz),
R-CO-NH-OH ⇄ RC(OH)=N-OH; hydroxylamine derivatives of carboxylic acids, including amino acids, formed by the action of hydroxylamine on carobxylic acids.
References in periodicals archive ?
Phase 2 trial of oral vorinostat (suberoylanilide hydroxamic acid, SAHA) for refractory cutaneous T-cell lymphoma (CTCL).
Allelopathic effect of hydroxamic acids from cereals on Avena sativa and A.
The biological activities of hydroxamic acids and similar ligands are known to be positively enhanced on complexation to bio-transition metal ions like copper (II), nickel (II) and oxovanadium IV (Aliyu and Nwabueze, 2008) and molybdenum (VI) (Aliyu, 2010).
Briefly, it consists of reacting the ester with hydroxylamine to produce a hydroxamic acid, which can be treated with a Iron(III) solution, producing a chromophore if esters are present with an absorption maxima around 505-520nm.
The same is true for the hydroxamic acids, the quinones, and the
Hydroxamic acids affecting barley yellow dwarf virus transmission by the aphid (Rhopalosiphum padi).
The organic thermochemistry of hydroxylamines, oximes, hydroxamic acids and their derivatives
Phenolic conjugates and hydroxamic acids were extracted from a 0.
Azaindole hydroxamic acids are hiv-1 integrase inhibitors
HDAC inhibitors can be divided into four main classes: cyclic tetrapeptides (I), short-chain fatty acids (II), hydroxamic acids (III), and benzamides (IV).
The third poster, entitled "The Design of Substituted Phenyl Hydroxamic Acids as Inhibitors of Histone Deacetylases," outlined the design of substituted phenyl hydroxamic acids as HDAC inhibitors.