hydroxamic acid


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hydroxamic acid

an inhibitor of urease and a chelating agent. See also acetohydroxamic acid.
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Table 1: Types of epigenetic drugs: Drugs Class 5-aza-cytidine (azacitidine), Nucleoside DNMTIs 5-aza-2-deoxycytidine (decitabine), 5-fluoro-2-deoxycytidine, Zebularine RG108 Non-Nucleoside DNMTIs MG98 Antisense Oligonucleotides Table 2: HDAC inhibitors: Drugs Class Valproic acid, Aliphatic acids Sodium phenylbutyrate, Pivaloyloxymethyl butyrate, Vorinostat Romidepsin Cyclic peptides Belinostat, Hydroxamic acids Panobinostat Entinostat, Benzamides Mocetinostat
The mechanism of the anti-tumor activity of the histone deacetylase inhibitor, suberoylanilide hydroxamic acid (SAHA).
Zn(II)-dependent histone deacetylase inhibitors: suberoylanilide hydroxamic acid and trichostatin A.
Histone deacetylase inhibitors: development of suberoylanilide hydroxamic acid (SAHA) for the treatment of cancers.
Resistance to the aphids Sitobion avenae and Rhopalosiphum padi in Gramineae in relation to hydroxamic acid levels.
Presence of a hydroxamic acid glucoside in wheat phloem sap, and
and British colleagues added an HDAC inhibitor called suberoylanilide hydroxamic acid to the drinking water of young mice genetically engineered to make mutated huntingtin protein.
An inhibitor of urease of any origin, hydroxamic acid, and a specific inhibitor, acyl phosphate, have been described (1).
Therefore, the carboxylic acid moieties were partially converted to hydroxamic acid moieties by reacting the carboxylic acid groups with hydroxylamine (ref.
Suberoylanilide hydroxamic acid (SAHA) holds promise as a first-generation drug for the prevention and treatment of familial frontotemporal dementia (FTD), a progressive, inherited neurodegenerative disease for which there is no treatment," said Joachim Herz, professor of molecular genetics and neuroscience at UT Southwestern and the study's senior author.