hydrophobic interaction

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Related to hydrophobic interaction: Hydrophobic Interaction Chromatography

hy·dro·pho·bic in·ter·ac·tion

interaction between uncharged substituents on different molecules without a sharing of electrons or protons; entropy-driven interaction.
Synonym(s): apolar interaction


1. pertaining to hydrophobia (rabies).
2. repelling water; insoluble in water; not readily absorbing water.

hydrophobic interaction
interaction of nonpolar (un-ionizable) hydrocarbon molecules forced together because of stronger water-water interaction.
hydrophobic signal peptides
15 to 30 amino acids located at or near the N-terminus of a protein that always includes a hydrophobic core of at least eight nonpolar amino acids, found in proteins that are synthesized on membrane bound ribosomes and destined for export from the cell.
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And, it should be remembered that this deadline had been set when the problems with the master cell bank and the challenge presented by the use of hydrophobic interaction chromatography could not have been foreseen.
This may be because that under high shear condition, the hydrophobic interactions can be disrupted, giving rise to a decrease in the apparent molecular weight, and hence a decrease in the solution viscosity, however, under low shear conditions the hydrophobic interchain associations will reform, restoring the high solution viscosity.
The (CBB) method (26) has been used to test the RO-CMC derivatives for hydrophobic interactions.
The observed shifts and variation in intensities of the composites also suggests the hydrophobic interactions between PVA and PVP as shown in Fig.
In addition, the gels formed by gelation of nanogel dispersions based on PNIPAAm have higher strengths because of the heterogeneous structures formed by hydrophobic interactions and hydrogen bonding between particles.
In the case of flexible polymer chains, such as hydrophobically modified polyacrylamides, the decrease in the reduced viscosity occurs because of the strong intramolecular hydrophobic interactions, which promote the polymer-polymer interactions in aqueous medium due to the decrease in the solvent quality.
The rest of the book considers the results of calorimetric studies of various types of biological macromolecules and their complexes; these studies have led to the reconsideration of widely accepted dogma on the roles of hydrogen bonding, hydrophobic interactions, and water in the formation of macromolecular structures.
Impact of ultra sound on hydrophobic interactions in solutions: ultrasonic retardation of benzoin condensation.
Cyclodextrins are well known for disrupting hydrophobic interactions in aqueous media.
The thermodynamic analysis of the TQ-HSA complex formation shows that the binding process is enthalpy driven and spontaneous, and that hydrophobic interactions are the predominant intermolecular forces stabilizing the complex.