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humanized antibody

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humanized antibody
Molecular medicine A recombinant DNA product which ↓ non-human monoclonal antibody immunogenicity, by transferring the hypervariable genes of rodent antibodies–which encode peptide segments capable of recognizing the desired epitope, into normal human genes. Cf Designer antibody.


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Cheshire, CT) jointly announced that the companies have entered into a definitive license agreement and settlement agreement that resolve the legal disputes between them relating to Alexion's humanized antibody, Soliris (eculizumab) and PDL's patents known as the Queen et al.
Actemra(R) (humanized anti-human IL-6 receptor monoclonal antibody) Actemra(R) is a humanized antibody to the human IL-6 receptor, and was created using genome engineering technology.
Zenapax is a humanized antibody created by PDL and developed and marketed by Hoffmann-La Roche, Inc.
 
 
 
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