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humanized antibody |
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humanized antibody Molecular medicine A recombinant DNA product which ↓ non-human monoclonal antibody immunogenicity, by transferring the hypervariable genes of rodent antibodies–which encode peptide segments capable of recognizing
the desired epitope, into normal human genes. Cf Designer antibody. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Actemra(R) is a humanized antibody to the human IL-6 receptor, and was created using genome engineering technology. Abstract #7534: A Humanized Antibody Against CD40 (SGN-40) is Well Tolerated and Active in Non-Hodgkin's Lymphoma: Results of a Phase I Study. The potential partners we are in active discussions with, along with our regulatory advisors and representatives from various regulatory agencies, have all indicated a strong preference for using a humanized antibody in further RIGScan development activities. |
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