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human monocytic ehrlichiosis

   Also found in: Encyclopedia 0.01 sec.
ehrlichiosis /ehr·lich·i·osis/ (ār-lik″e-o´sis) a febrile illness due to infection with bacteria of the genus Ehrlichia.
human granulocytic ehrlichiosis  a sometimes fatal human ehrlichiosis caused by an Ehrlichia equi –like species, characterized by flulike symptoms and involving predominantly neutrophils.
human monocytic ehrlichiosis  a sometimes fatal human ehrlichiosis caused by Ehrlichia chaffeensis, characterized by flulike symptoms and involving predominantly fixed tissue mononuclear phagocytes.

human monocytic ehrlichiosis.
human monocytic ehrlichiosis
Infectious disease An infection by Ehrlichia chaffeensis Vector Lone Star tick–Amblyomma americanum, possibly also Dermacentor variabilis Reservoir Deer, possibly dogs or others Regions US, Europe, Africa Clinical Fever, malaise, headache, myalgia, rigors, sweating, anorexia, arthralgia, N&V, pharyngitis, rash, cough, diarrhea; with progression of HME, fever, headache, myalgia, anorexia, and arthralgia become more intense Lab CSF pleocytosis, E chaffeensis inclusions in monocytes, spleen and other tissues, BM hyperplasia–58%, hypoplasia–17% Diagnosis Romanovsky stains of circulating monocytes, EM, indirect immunofluorescence, PCR Complications Meningitis, interstitial pneumonia, GI and pulmonary hemorrhage, disseminated hemorrhage. Cf Human granulocytic ehrlichiosis.


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Human Monocytic Ehrlichiosis (HME) is a vector-borne disease transmitted through the bite of Ixodid ticks carrying the obligate intraleucocytic bacterium Ehrlichia chaffeensis.
Recognition and emergence of human tickborne ehrlichiosis are recent and continuing events, beginning with human monocytic ehrlichiosis and human granulocytic ehrlichiosis, reported first in the United States in 1987 and 1994, respectively.
Human monocytic ehrlichiosis due to Ehrlichia chaffeensis: how do we count the cases?
 
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