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human insulin

   Also found in: Acronyms 0.02 sec.
human insulin
n.
A protein that has the normal structure of insulin produced by the human pancreas but that is prepared by recombinant DNA techniques and by semisynthetic processes.

human insulin,
a biosynthetic product manufactured from Escherichia coli by recombinant deoxyribonucleic acid technology. The advantage of human insulin is that it eliminates allergic reactions that occur with the use of animal insulins. See also insulin, def. 2.


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The immune system would attack pancreas islet cells that make human insulin, which resembles bovine insulin, and would produce antibodies.
Synthetic human insulin (eg, Humulin), derived from a recombinant deoxyribonucleic acid process in Escherichia coli, is now routinely used.
The perceived shortage triggered a race to mass-produce human insulin by synthesizing a human insulin gene.
 
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