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human herpesvirus 8 |
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human herpesvirus 8, a virus in the family Herpesviridae that has been implicated as the causative agent of Kaposi's sarcoma, a rare form of cancer occasionally seen in AIDS patients, and primary effusion lymphoma. The predominant route of transmission is sexual activity. The virus may also be transmitted through blood contact in IV drug use. Treatment is currently experimental. Also called Kaposi's sarcoma-associated herpesvirus. See also Kaposi's sarcoma, primary effusion lymphoma. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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In 2001, we conducted a survey of Ugandan children with sickle cell disease and their mothers and found that human herpesvirus 8 infection was associated with transfusion in these children (5). Human herpesvirus 8 (HHV8), shed mainly in saliva, is important in KS development. Some NHL in HIV-infected patients has been attributed to deficient immune surveillance of oncogenic herpesviruses, such as Epstein-Barr virus (EBV) and human herpesvirus 8 (HHV-8), or perhaps to chronic antigenic stimulation and defective immune regulation. |
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