housekeeping genes


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house·keep·ing genes

genes that are generally always expressed and thought to be involved in routine cellular metabolism.

housekeeping genes

Constitutive genes, genes that provide the basic routine functions required by all cells for their sustenance.

housekeeping genes

GENES governing the fundamental metabolic processes of CELLS and that are EXPRESSED in most cell types.
References in periodicals archive ?
Housekeeping genes as internal standards: use and limits.
To identify and validate housekeeping genes in the brains of the desert locust, schistocerca gregaria Forsskal (Acrididae) under various developmental conditions, Van Hiel et al.
Effect of experimental treatment on housekeeping gene expression: validation by real-time, quantitative RT-PCR.
pneumoniae strains to compare them and confirm clonal and pathogenicity relationships through housekeeping gene analysis.
This analysis uses the difference between the housekeeping gene and the control sample as [sup.
The idea of a housekeeping gene is that it should be uniformly expressed throughout all the experimental or environmental conditions of a given system (14).
The researchers found that these induced genes, in contrast to the 'clueless' housekeeping genes, act in an expected (well-regulated) way.
Seven genes having high similarity to housekeeping genes from different Clostridium species were identified.
Transposable elements, the promoter regions of housekeeping genes, and cis-acting regulatory elements of imprinted genes are three key epigenetic susceptibility targets containing CpG sites that are normally methylated, unmethylated, and differentially methylated, respectively.
However, this may not be the case in all microarray experiments, and thus other genes such as housekeeping genes (with constant expression) may facilitate controlling other sources of variability (Yang et al.