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hot nodule

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hot nodule
Nuclear medicine A focal ↑ in radioisotope uptake on a 123I scintillation scan in a solid organ–eg, liver or thyroid, seen by immunoscintigraphy; thyroid HNs often correspond to toxic nodular or multinodular goiter, as functional thyroid lesions suppress TSH synthesis; HNs are rarely malignant. See Scintigraphy. Cf Cold nodule, Warm nodule.


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A hot nodule can be diagnosed using a radioactive iodine scanner test.
Its role in identifying hot nodules and areas of autonomous thyroid function is well established.
Overall, a cold nodule was associated with a significantly higher incidence of malignancy than was a hot nodule (sensitivity = 91%; specificity = 19%; accuracy = 38%; [chi square] = 7.
 
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