hormonal manipulation

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hormonal manipulation

1. The treatment of diseases, e.g., endometriosis, or endocrine-responsive tumors (such as breast and prostate cancer) with drugs that block the action of hormones or releasing factors. Synonym: endocrine manipulation

2. The use of hormones to affect menstrual cycles or fertility.

3. The use of hormones like testosterone to enhance athletic performance or increase muscle mass.

See also: manipulation

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References in periodicals archive ?

The ability of GTx-758 to reduce serum free testosterone well below levels achieved with standard LHRH therapy may result in improved tumor control in first line therapy as well as allow for the use of GTx-758 for second line hormonal manipulation in men with advanced prostate cancer," said Ronald A.

GTx Announces That GTx-758, a Novel Oral Selective Estrogen Receptor Alpha Agonist Being Developed to Treat Advanced Prostate Cancer, Induced Medical Castration in a Phase II PK/PD Clinical Trial

Before the advent of non-surgical endoluminal therapies for pelvic congestion syndrome medical therapy with hormonal manipulation was the first-line therapy.

Non surgical treatment now available for women with lower abdominal pain

1] Hormonal manipulation, based on androgen deprivation and anti-androgen therapy, is the initial cornerstone of medical management of locally advanced or metastatic prostate cancer.

Chemotherapy for prostate cancer: Clinical practice in Canada

Hormonal manipulation may prove to provide relief for women with chronic, cyclic irritable bladder symptoms, results of a University of Washington pilot study suggested.

GnRH agonists may offer novel option for interstitial cystitis. (Cyclic Irritable Bladder Symptoms)

Since the growth of prostate cancer is testostecrone-dependent (approximately 95% of testosterone is produced by the testes, with the remainder coming from the adrenals), hormonal manipulation has been the mainstay of plliative treatment.