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homovanillic acid |
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homovanillic acid /ho·mo·va·nil·lic ac·id/ (ho″mo-vah-nil´ik) a major terminal urinary metabolite, converted from dopa, dopamine, and norepinephrine.
homovanillic acid [hō′mōvənil′ik] an acid that is produced by the normal metabolism of dopamine and that may occur at an elevated level in urine in association with tumors of the adrenal gland. Its normal accumulation in a 24-hour collection urine sample is 15 mg. homovanillic acid (hō´mōv n an acid that is produced by normal metabolism of dopamine and may be elevated in the urine in association with tumors of the adrenal gland. homovanillic acid HVA Physiology A major dopamine metabolite used to synthesize epinephrine and norepinephrine and excreted in urine; HVA is usually measured with the major catecholamines and other catecholamine metabolites; HVA is ↑ in
neuroblastoma and ganglioneuroma Ref range 0-15 mg/24 hr urine. See Hypertension, Pheochromocytoma. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Urinary homovanillic acid (HVAU), one of the end-products of dopamine metabolism, was assayed in urine using isocratic HPLC, whereas serum prolactin (PRLS), whose secretion is under control of the dopaminergic system, was measured in serum by chemiluminescent enzyme immunoassay, as previously described (Alvarez Leite et al. Then, they allowed the hydrogen peroxide to react with homovanillic acid to form a fluorescent compound. Pharmacological Effects of Methylphenidate on Plasma Homovanillic Acid and Growth Hormone. |
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