homolog


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hom·o·logue

, homolog (hom'ō-log),
A member of a homologous pair or series.
[homo- + G. logos, word, ratio, relation]

homolog

or

homologue

(hŏm′ə-lôg′, -lŏg′, hō′mə-)
n.
Something that is homologous, as an organ, body part, or gene.

homolog

[hom′əlog]
Etymology: Gk, homos, same
1 any organ corresponding in function, origin, and structure to another organ, as the flippers of a seal correspond to human hands.
2 (in chemistry) one of a series of compounds, each formed by an added common atom or atom combination. For example, CH4, methane, is followed by C2H6, ethane, with the addition of a CH2 group. Also spelled homologue. Compare analog. homologous, adj.

homologue

, homolog (hom′ŏ-log″) [Gr. homologos, agreeing, of one mind]
1. An organ or part common to several species.
2. One that corresponds to a part or organ in another structure.
3. In chemistry, any member of a series that resembles the other members in action and general structure but has a constant compositional difference such as a methyl, CH3, group.
References in periodicals archive ?
Expression of CEN is dependent on expression of FLO, the homolog of UNI (Bradley et al.
in addition to their potency in apoptosis control, evidenced by the disastrous in vivo consequences of Bcl2 gene translocation into immunoglobulin transcription control sequences, their importance is further underscored by the fact that mammalian viruses appear to have evolved the capacity to manipulate the activities of Bcl-2 family members by expressing their own Bcl-2 homologs.
Additional mutations identified in this cohort were mapped to the following genes: APC (n = 3), PIK3CA (n = 2), ataxia telangiectasia mutated (ATM) (n = 2), and neuroblastoma RAS viral (v-ras) oncogene homolog (NRAS) (n = 1).
Unlike two-headedness, this condition does not result from partially fused twins; it stems from problems early on in embryonic development connected to a protein signal called sonic hedgehog homolog, or SHH.
At the molecular level, COC administration resulted in a significant attenuation of PTEN (phosphatase and tensin homolog deleted on chromosome 10) and upregulation of phospho-Akt and c-Raf levels in the heart.
BRaf (v-raf murine sarcoma viral oncogene homolog B1) is a serine/threonine kinase that belongs to the Ras-Raf-MEK-ERK pathway involved in the transduction of mitogenic signals from the cell membrane to the nucleus.
Collins gave the example of a mutation in a gene called MutL homolog 1, colon cancer, nonpolyposis type 2 (MLH1) that's known to increase a person's lifetime risk of developing colon cancer from an average of about 6 percent to around 60 percent.
There was also a group of genes that were involved in the pathogenesis of vascular disease, including those associated with the clotting independent signaling of F3, which included v-fos FBJ murine osteosarcoma viral oncogene homolog (FOS, Unigene accession no.
Participating companies would commit to reduce and work toward ultimately eliminating facility emissions and product content of PFOA, PFOA precursors and related higher homolog chemicals.
In Drosophila, a PLCb4 homolog interacts with clock proteins and underlies the mechanism for an oscillation in visual sensitivity.
To test this hypothesis, we isolated and investigated the function of the zebrafish gene zASIP, a homolog of the ASIP/Bazooka/Par-3 gene that is conserved from worms to humans.