Cobalamin C (cblC) disease is the most common type of MMA and is characteristically concurrent with homocystinemia
(HCY) due to impaired synthesis of two active forms of cbl, namely adenosylcobalamin (AdoCbl) and methylcobalamin (MeCbl).
Microspherophakia is usually associated with systemic disorders such as Weill-Marchesani syndrome (WMS), homocystinemia
, Marfan syndrome, Alport syndrome and Klinefelter syndrome.
as an independent risk factor in the Chinese population at a high risk of coronary artery disease.
An increase in the serum level of vWF was observed in diseases that cause endothelial damage such as vasculitis, (3) systemic lupus erythematosus, rheumatoid arthritis, (4-6) scleroderma diabetes mellitus, (8-10) glomerulonephritis, (11) viral infections, toxemia of pregnancy, homocystinemia
, myocardial infarction, and thromboembolic events.
does not appear to be a risk factor solely for ischemic heart disease either.