Lower amounts of collagen crosslinks have been found in patients who have homocysteinuria
Lower amounts of collagen cross-links have been found in patients who have homocysteinuria
This discovery was extrapolated from the association of CVD found in patients diagnosed with homocysteinuria
, a rare inborn autosomal recessive disease complicated by early cardiac death (Taylor-Chinn, 2000).
Dietary treatment does not appear to help people with highly elevated levels or children born with a genetic defect which causes homocysteinuria
or extremely elevated levels.
Kilmer McCully, a pathologist at Harvard, while doing an autopsy on a two-month-old infant who had died of homocysteinuria
, found extensive damage to the arteries with plaque formation as one might see in someone in the later decades of life.