homeotic gene


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Related to homeotic gene: Homeotic mutation

homeotic gene

(hō′mē-ŏt′ĭk)
n.
Any of various genes that determine the type or location of a body part during an organism's development, especially in the early embryonic development of vertebrates.

homeotic gene

one of a group of genes involved in DEVELOPMENT and DIFFERENTIATION, controlling the formation of whole organisms or body parts in animals and plants. Homeotic genes contain the homeobox, which encodes a PROTEIN DOMAIN that is capable of binding to DNA. Each homeotic gene regulates EXPRESSION of a set of other genes that direct development of a body part, such as an insect wing, antenna, leg. A TRANSCRIPTION factor, specified by the homeotic gene, binds to the PROMOTER of the set of genes that encodes the specific structure.

Many organisms have similar sets of homeotic genes. Dysfunction of these genes can result in developmental abnormalities.

References in periodicals archive ?
LEAFY a homeotic gene that regulates inflorescence development in Arabidopsis.
Many homeotic genes have been identified and characterized, and most belong to the plant MADS-box regulatory gene family (Purugganan et al.
The MADS-box floral homeotic gene lineages predate the origin of seed plants: Phylogenetic and molecular clock estimates.
Characterization of MADS homeotic genes in the fern Ceratopteris richardii.