homeobox gene


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Related to homeobox gene: Hox gene

homeobox gene

n.
One of a group of genes with a characteristic sequence of nucleotides coding an amino acid sequence that functions in binding to DNA. Homeobox genes are involved in the formation of bodily segmentation during embryologic development.

homeobox gene

Any transcription factor that regulates the growth, differentiation, replication, and movement of cells in the body. These genes influence both normal and abnormal embyological development and the development or suppression of malignant tumors.
See also: gene
References in periodicals archive ?
HOM/HOX homeobox genes are present in hydra (Chlorohydra viridissima) and are differentially expressed during regeneration.
elegans thermoregulatory pathway by the ttx-3 LIM homeobox gene.
Sequential activation of HOX2 homeobox genes by retinoic acid in human embryonal carcinoma cells.
Homeobox genes have been found in all metazoan phyla that have been surveyed, as well as in plants and fungi (reviewed in Burglin, 1994).
The homeobox gene Hhex is essential for proper hepatoblast differentiation and bile duct morphogenesis.
In the present study, 22 homeobox gene fragments from five bivalve species belonging to five different Bivalvia families were identified, and then these homeodomain sequences were compared with those available from other bivalve molluscs.
Involvement of the HLXB9 homeobox gene in Currarino syndrome," American Journal of Human Genetics, vol.
The homeobox gene Pitx2: mediator of asymmetric left-right signaling in vertebrate heart and gut looping.
PTEN and TNF-alpha regulation of the intestinal-specific Cdx-2 homeobox gene through a PI3K, PKB/Akt, and NF-kappaB-dependent pathway.
Hence, disruption of homeobox gene expression, a downstream target of the AHR/TCDD axis, is potentially a major component of the inhibition of cardiomyocyte function by TCDD.
Negative auto regulation of the Arabidopsis homeobox gene ATHB-2.