homeobox gene

Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.

Related to homeobox gene: Hox gene

homeobox gene

One of a group of genes with a characteristic sequence of nucleotides coding an amino acid sequence that functions in binding to DNA. Homeobox genes are involved in the formation of bodily segmentation during embryologic development.

homeobox gene

Any transcription factor that regulates the growth, differentiation, replication, and movement of cells in the body. These genes influence both normal and abnormal embyological development and the development or suppression of malignant tumors.

See also: gene

Mentioned in ?

References in periodicals archive ?

Expression pattern of the rat lim-l homeobox gene suggests a dual role during kidney development.

Frog Lim-1-like Protein Is Expressed Predominantly in the Nervous Tissue, Gonads, and Early Embryos of the Bivalve Mollusc Mytilus galloprovincialis

HOM/HOX homeobox genes are present in hydra (Chlorohydra viridissima) and are differentially expressed during regeneration.

Evolution of head development

elegans thermoregulatory pathway by the ttx-3 LIM homeobox gene.

A common theme for LIM homeobox gene function across phylogeny?

Sequential activation of HOX2 homeobox genes by retinoic acid in human embryonal carcinoma cells.

Exogenous retinoic acid during gastrulation induces cartilaginous and other craniofacial defects in Fundulus heteroclitus

Homeobox genes have been found in all metazoan phyla that have been surveyed, as well as in plants and fungi (reviewed in Burglin, 1994).

Homeoboxes in sea anemones (Cnidaria; Anthozoa): a PCR-based survey of Nematostella vectensis and Metridium senile

The homeobox gene Hhex is essential for proper hepatoblast differentiation and bile duct morphogenesis.

Development of Liver and Pancreas

In the present study, 22 homeobox gene fragments from five bivalve species belonging to five different Bivalvia families were identified, and then these homeodomain sequences were compared with those available from other bivalve molluscs.

Hox, Parahox, EHGbox, and NK genes in bivalve molluscs: evolutionary implications

Involvement of the HLXB9 homeobox gene in Currarino syndrome," American Journal of Human Genetics, vol.

Fatal Meningitis in a 14-Month-Old with Currarino Triad

The homeobox gene Pitx2: mediator of asymmetric left-right signaling in vertebrate heart and gut looping.

Genetic Characteristics and Evolution of Pitx2 in Sinistral Tongue Sole, Cynoglossus semilaevis and Dextral Stone Flounder, Kareius bicoloratus

PTEN and TNF-alpha regulation of the intestinal-specific Cdx-2 homeobox gene through a PI3K, PKB/Akt, and NF-kappaB-dependent pathway.

CDX2 Inhibits Invasion and Migration of Gastric Cancer Cells by Phosphatase and Tensin Homologue Deleted from Chromosome 10/Akt Signaling Pathway

Hence, disruption of homeobox gene expression, a downstream target of the AHR/TCDD axis, is potentially a major component of the inhibition of cardiomyocyte function by TCDD.

Disruption of aryl hydrocarbon receptor homeostatic levels during embryonic stem cell differentiation alters expression of homeobox transcription factors that control cardiomyogenesis

Negative auto regulation of the Arabidopsis homeobox gene ATHB-2.

Genetic Characterization of Different Tomato Varieties on the Basis of atpB Gene Promoter