homeobox


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ho·me·o·box

(hō'mē-ō-boks),
A highly conserved DNA sequence of about 180 base pairs near the 3' end of specific homeotic genes; it encodes a DNA-binding domain that allows the homeobox proteins to bind to and regulate gene expression in development.
Synonym(s): homeodomain

homeobox

(hō′mē-ə-bŏks′)
n.
A sequence of DNA encoding a protein structure that binds to specific parts of DNA and affects transcription of DNA into RNA.

homeobox

a conserved DNA motif of about 180bp encoding a protein domain (approximately 60 amino acids) that binds to DNA. The homeobox is a characteristic of HOMEOTIC GENES and is found in most EUKARYOTES.
References in periodicals archive ?
Hake and others have now used the Knotted homeobox as a probe to identify more than a dozen other homeobox genes in corn, plus some in tomatoes, barley, peas, and rice.
The Pitx homeobox gene in Bombyx mori: regulation of DH-PBAN neuropeptide hormone gene expression.
Oftalmik gelisimde onemli olan iki homeobox gen ailesi, PAX ve HOX gen aileleridir.
A number of schizencephaly patients including 2 brothers are heterozygous for germline mutations in the homeobox gene EMX2.
Homeobox genes: their function in Drosophila segmentation and pattern formation.
The intestinal CDX2 homeobox gene is a target of PTEN/phosphatidylinositol 3-kinase signaling and tumor necrosis factor a signaling via Nuclear Factor ?
Hemen daima 11p13 bolgesinde yer alan bir homeobox transkripsiyon faktoru olan PAX6 mutasyonlariyla iliskilidir, yuksek penetrans ve degisken ekspresyon gosteren otozomal dominant kalitim patemi gosterir.
6% of identified proteins belonged to this group, including homeobox protein DLX-6 (P56179), sickle tail protein homolog (Q5T5P2), and fetuin-A (P02765) (Graham 2002; Karamessinis et al.
La organogenesis del pancreas consiste en una cascada secuencial de eventos de induccion en asociacion con la activacion de factores de transcripcion especificos, siendo el mas importante el Pdx1 (pancreas duodenum homeobox 1) (Wang et al.
Does the high gene density in the sponge NK homeobox gene cluster reflect limited regulatory capacity?
La familia de genes MSX (3,4), una familia de genes homeobox de vertebrados homologos a msh de la Drosophila, constituye una de las familias mas conservadas evolutivamente en las diferentes especies (3,5) y se encuentra relacionada con el control de las relaciones epitelio-mesenquima.
The mice have a mutated version of one of the homeobox, or Hox, genes, which scientists have implicated in embryo development.