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homeobox gene
(redirected from homeobox)

   Also found in: Dictionary/thesaurus, Acronyms, Encyclopedia, Wikipedia 0.01 sec.
ho·me·o·box gene (hm--bks)
n.
A DNA sequence in a homeotic gene that encodes for a specific sequence of amino acids in a protein.

gene,
(ho´meoboks”),
n a gene containing a DNA sequence called the homeobox, which is very similar between species and encodes a DNA-binding domain in the resulting protein molecule. Homeobox genes usually play a role in controlling development of the organism.
gene locus,
gene, sex-linked,
n a gene located in a sex chromosome.
gene therapy,
n a procedure that involves injection of “health genes” into the bloodstream of a patient to cure or treat a hereditary disease or similar illness.


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According to background information in the report, the SHOX gene (short stature homeobox gene) is responsible for the normal growth of bones, and is often mutated in short-stature patients-no more than 160 cm of final height in men, and 150 cm in women.
Case Western Reserve University (Cleveland, OH) has patented a novel growth arrest homeobox gene and the nucleotide sequences determined in both the rat and the human.
The mice have a mutated version of one of the homeobox, or Hox, genes, which scientists have implicated in embryo development.
 
 
 
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