holoprotein


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hol·o·pro·tein

(hol'ō-prō'tēn),
A complete protein, that is, apoprotein plus metal ion and/or prosthetic group.

holoprotein

a complete protein with its prosthetic group.
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The genetic mutations causing Wilson disease impair the hepatic incorporation of copper into apoceruloplasmin, leading to a reduction in the total serum ceruloplasmin concentration due to the instability of the apoceruloplasmin relative to the holoprotein with its full complement of copper [24,25].
Herms, "Involvement of presenilin holoprotein upregulation in calcium dyshomeostasis of Alzheimer's disease," Journal of Cellular and Molecular Medicine, vol.
To ascertain sites where introduction of amino acid residues would be tolerated without affecting folding of the polypeptides and assembly into holoprotein, methionine residues were introduced into different regions of the Gy1 gene (Utsumi et al.
13) in which apoproteins are first separated from holoproteins and then the TC fraction of the holoproteins is directly measured by ELISA.
They first separated holoproteins from apoproteins by use of cobalamin-coated magnetic beads and then directly assayed the TC fraction of the holoproteins by ELISA.