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holoenzyme

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holoenzyme /holo·en·zyme/ (-en´zīm) the active compound formed by combination of a coenzyme and an apoenzyme.
hol·o·en·zyme (hl-nzm, hl-)
n.
An active, complex enzyme consisting of an apoenzyme and a coenzyme.

holoenzyme
[hol′ō·en′zīm]
Etymology: Gk, holos + en, in, zymos, ferment
a complete enzyme-cofactor complex that gives rise to full catalytic activity.

holoenzyme
an enzyme which contains several different subunits and retains some activity even when one or more of the subunits is missing.


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Trewhella, Quaternary Structures of a Catalytic Subunit-Regulatory Subunit Dimeric Complex and the Holoenzyme of the cAMP-Dependent Protein Kinase by Neutron Contrast Variation, J.
Supporting that notion, Scully and his colleagues report in the May 27 Proceedings of the National Academy of Sciences that BRCA1 may be part of RNA polymerase II holoenzyme, a large collection of proteins used to create strands of RNA, the first step in assembling a gene's protein.
Supporting that notion, Scully and his colleagues report in the May 27 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES that BRCA1 may be part of RNA polymerase II holoenzyme, a large collection of proteins used to create strands of RNA, the first step in assembling a gene's protein.
 
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