historical control

A control group that is chosen from a group of patients who were observed at some time in the past or for whom data are available through records. Historical controls are used for comparison with subjects being treated or assessed concurrently

historical control

Epidemiology A control group that is chosen from a group of patients who were observed at some time in the past or for whom data are available through records; HCs are used for comparison with subjects being treated concurrently. See Control.
References in periodicals archive ?
Median survival time was 956 days compared to 423 days for a historical control group.
The results suggest a meaningful and favorable difference to date in recovery of arm, hand and finger function in patients treated with the 10 million cell dose of AST-OPC1 as compared to the level of expected rates of spontaneous recovery shown from historical control data of a closely matched patient population.
The initial sample for the historical control group was 174 FW encounters.
I think this is encouraging if you compare [these patients] to historical control patients with brain metastases," said Dr.
Historical control failings, which led to excessive risk exposures and underwriting losses outside of the approved risk appetite, have now been resolved.
The authors suggested the post-implantation loss, the decreased body weights and the incident of dead foetus are well within the historical control data range and as such the no-observed-effect-level (NOEL) was above 1225mg/kg/day for the dams and the foetuses, however these findings should not be discounted.
The patients in the present study were compared (chi-squared test and t test) with two historical control groups of patients with traumatic hyphema who had previously been treated; one group with oral placebo and the other one with oral tranexamic acid at our department.
The study compared the outcomes of trials for the same treatments and found that 79% of clinical trials with a historical control group showed a benefit over control, while only 20% of trials with a direct control group showed a benefit over control.
This study examines the rate of late-preterm birth in a hypnosis group (directed to all women) and a historical control group.
Nurses' notes were reviewed for the 6-month preassault period and a 6-month historical control period during which the patient had been clinically stable.

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