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historical control

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historical control
Epidemiology A control group that is chosen from a group of patients who were observed at some time in the past or for whom data are available through records; HCs are used for comparison with subjects being treated concurrently. See Control.


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Although we cannot prove that early intervention with corticosteroids prevented RADS, we think that the prompt prophylactic treatment might have expedited symptom resolution and prevented RADS, on the basis of previous historical control data.
The addition of consolidation therapy with docetaxel improved the median survival from 15 months in historical control subjects to 26 months in patients who completed concurrent cisplatin/etoposide-radiation therapy (68, 69).
Because the current study's historical control group involved manual paperbased chart documentation by nursing staff, the study could not electronically collect historical control population variables such as insulin dose, nutrition source, and protocol compliance.
 
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