histone /his·tone/ (his´tōn) a simple protein, soluble in water and insoluble in dilute ammonia, found combined as salts with acidic substances, e.g., the protein combined with nucleic acid or the globin of hemoglobin.
histone
his·tone (h s t n )n. Any of several small simple proteins that are most commonly found in association with the DNA in chromatin and contain a high proportion of basic amino acids. |
histone
[his′tōn]
Etymology: Gk, histos, tissue
any of a group of strongly basic, low-molecular weight proteins that are soluble in water and insoluble in dilute ammonia and combine with DNA to form nucleoproteins. They are found in the nucleus of eukaryotic cells, where they form a complex with DNA in the chromatin and function in regulating gene activity. See also nucleosome.
histone
a simple protein, soluble in water and insoluble in dilute ammonia, found combined as salts with acidic substances, such as in DNA where they have a structural and functional role.
histone acetylase, histone deacylase
enzymes responsible for the reversible acylation of four lysine residues near the N-terminus of histone H4.
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