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histocompatibility complex

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histocompatibility complex,
a group of genes whose products determine the compatibility of tissues or organs transplanted from one individual to another of the same species or from one species to another. The histocompatibility complex of proteins is found on the plasma membrane cells and helps identify tissues as "self" or foreign. In humans the major histocompatibility complex contains 50 genes on the short arm of chromosome number 6. See also HLA complex.


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The researchers scanned the genome of cytomegalovirus and found a microRNA that targets a gene called major histocompatibility complex class I-related chain B (MICB).
The database contains scientific and clinical data on the relationship between major histocompatibility complex (MHC) genes and transplantation.
1) Among the genetic loci most strongly implicated in susceptibility to SLE are various immune-response genes, including the major histocompatibility complex (MHC), MHC-linked, and non-MHC genes.
 
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