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high-grade squamous intraepithelial lesion

   Also found in: Acronyms 0.01 sec.
high-grade squamous intraepithelial lesion
Gynecology
A lesion defined by cytologic findings–cells occur singly or in syncytia-like sheets, ↑ nuclear:cytoplasmic ratio, nuclear hyperchromasia that translate into moderate-to-severe dysplasia–CIN 2 to 3/carcinoma in situ of the uterine cervix–a diagnosis made on histology of biopsied tissue, a precancerous lesion. Cf Low-grade squamous intraepithelial lesion.
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High-grade squamous intraepithelial lesion (HSIL) means there are a larger number of more abnormal pre-cancerous cells.
South African women with cervical cancer often present late and have ... by Botha, M.H. "Hennie" / CME: Your SA Journal of CPD
6 Thus, any single Pap test event is only 50% sensitive for detecting high-grade squamous intraepithelial lesion (HSIL) or invasive carcinoma.
ProEx C Immunocytochemistry and High-Risk Human Papillomavirus DNA ... by Momin T Siddiqui and Kelly Hornaman and Cynthia Cohen and Aziza Nassar / Archives of Pathology & Laboratory Medicine
To highlight the significance of positive margins and extent of positive margins of the cervical LEEP biopsies in predicting the persistence of high-grade squamous intraepithelial lesion and to provide suggestions for reporting margins in cervical LEEP biopsies.
Significance of margin and extent of dysplasia in loop electrosurgery ... by Tyler, Lisa N.; Andrews, Nancy; Parrish, Rudolph S.; Hazlett, Linda J.; Korourian, Soheila / Archives of Pathology & Laboratory Medicine
 
 
 
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