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high-grade squamous intraepithelial lesion

   Also found in: Acronyms 0.01 sec.
high-grade squamous intraepithelial lesion
Gynecology
A lesion defined by cytologic findings–cells occur singly or in syncytia-like sheets, ↑ nuclear:cytoplasmic ratio, nuclear hyperchromasia that translate into moderate-to-severe dysplasia–CIN 2 to 3/carcinoma in situ of the uterine cervix–a diagnosis made on histology of biopsied tissue, a precancerous lesion. Cf Low-grade squamous intraepithelial lesion.


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As part of a College of American Pathologists Q-Probes program, participants from 68 laboratories were asked to retrospectively identify 50 consecutive Pap tests with an interpretation of ASC-US or atypical squamous cells cannot exclude high-grade squamous intraepithelial lesion (ASC-H) in which HPV testing was ordered.
MODELS A and B--Low-grade squamous intraepithelial lesion (LSIL); high-grade squamous intraepithelial lesion (HSIL) MODEL A Correct Current Grid - 10-Slide Test, based on a 100-point system Response?
high-risk human papillomavirus was detected in 50% of cases of high-grade squamous intraepithelial lesion (HSIL)
 
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