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General term for enzymes hydrolyzing N-acetylhexose (for example, N-acetylglucosamine) residues from gangliosidelike oligosaccharides. At least four specific enzymes carrying out this type of reaction are known: α-N-acetyl-d-galactosaminidase, α-N-acetyl-d-glucosaminidase, β-N-acetyl-d-hexosaminidase, and β-N-acetyl-d-galactosaminidase, each being specific for the configuration and type of sugar included in the name.
1. any of the enzymes that cleave hexosamines or acetylated hexosamines from gangliosides or other glycosides.
2. a specific hexosaminidase acting on keratan sulfate and ganglioside GM2 and related compounds.
General term for enzymes cleaving N-acetylhexose residues from gangliosidelike oligosaccharides.
an enzyme that catalyzes the cleavage of hexose from ganglioside GM2. Occurs in two forms, A and B. Deficiency occurs in GM2gangliosidosis of dogs, cats and pigs.