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hexokinase |
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hexokinase /hexo·ki·nase/ (hek″so-ki´nās) an enzyme that catalyzes the transfer of a high-energy phosphate group to a hexose, the initial step in the cellular utilization of free hexoses. The enzyme occurs in all tissues as various isozymes with varying specificities; the liver isozyme (type IV) is specific for glucose and is often called glucokinase.
hexokinase [hek′səkī′nās] Etymology: Gk, hex, six, glykys, sweet, kinein, to move, ase, enzyme a transferase enzyme present in all tissue that catalyzes the transfer of a phosphate group from adenosine triphosphate to glucose 6-phosphate. It is also found in yeast. hexokinase [hek″so-ki´nās] an enzyme that catalyzes the transfer of a high-energy phosphate group of a donor to d-glucose, producing d-glucose-6-phosphate.
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Serum fasting glucose concentrations were measured using the hexokinase method, with measurements performed in duplicate on an auto-analyzer (Leon et al. 7) The enzyme performing this task in cancers is hexokinase II (HK II), which is elevated in cancer cells. 3) [FIGURE 5 OMITTED] In these conditions, ADP for the ATP resynthesis in the mitochondrial matrix is supplied exclusively by the reaction of MtCK isoform in the mitochondrial intermembrane space, which enables to determine the rate of this particular reaction avoiding possible contributions from other CK isoforms as well as from the hexokinase reaction (Gellerich and Saks, 1982). |
hexokinase |
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