However, it was necessary for the insulin to take on a hexameric
form in order to have physical stability and an acceptable injection volume.
23) Telomeres cap the ends of chromosomes and consist of hexameric
TTAGGG repeats and the protective 'shelterin' protein complex.
43-50) NS1 is a glycosylated protein that exists as multiple forms: a membrane-bound intracellular dimer involved in the viral replication complex, a GPI-linked form at the plasma membrane, or a hexameric
form secreted from the infected cell.
12-25 The hexameric
Cx43 protein complex connexon, both as a gap junction and as a hemichannel, forms large-conductance ion channel with chemical gating similar to the Bcl-2 channels.
Telomeres are complexes of hexameric
repeats at the distal end of chromosomes where they provide stability and protection to the coding DNA.
2013) on a purified hexameric
2,3-ris-procyaninidin [4[beta]-8]-linked OPC showed the induction of eNOS and Akt phosphorylation accounted for vascular endothelium dependent relaxation in porcine coronary arteries and the plasma concentration of the vasoconstrictor endothelin-1 decreased by 10%.
Adiponectin is secreted by adipocytes which exist as oligomers, including trimeric (low molecular weight), hexameric
(middle molecular weight), and high molecular weight (HMW) complexes and globular adiponectin.
As discussed above, the pentameric and hexameric
oligomers may be the building blocks of the more toxic decameric and dodecameric complexes.
R55H, G84R, and G90S variations did not disturb adiponectin trimeric and hexameric
formations but obstructed their multimerization.
As a benchmark, we will tackle the interaction mode of the ring-shaped hexameric
DnaB helicase with its partner DnaC, an assembly that controls the origin of the DNA replication in E.
Tenascin-C is a large (180-300 kDa), hexameric
multidomain glycoprotein and located mainly in the ECM.
A recursive criteria for minimum repeat number and motif length was set for 5 monomeric 5 dimeric 3 trimeric 3 tetrameric 2 pentameric and 2 hexameric