heterozygosity


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Related to heterozygosity: Loss of heterozygosity

heterozygosity

 [het″er-o-zi-gos´ĭ-te]
the state of having different alleles in regard to a given character. adj., adj heterozy´gous.

het·er·o·zy·gos·i·ty

, heterozygosis (het'ĕr-ō-zī-gos'i-tē, -zī-gō'sis),
The state of being heterozygous.
[hetero- + G. zygon, a yoke]

heterozygosity

/het·ero·zy·gos·i·ty/ (het″er-o-zi-gos´ĭ-te) the state of possessing different alleles at a given locus in regard to a given character.heterozy´gous

het·er·o·zy·gos·i·ty

, heterozygosis (het'ĕr-ō-zī-gos'i-tē, -zī-gō'sis)
The state of being heterozygous.
[hetero- + G. zygon, a yoke]

heterozygosity

The state of possessing two different ALLELES for one or more genes. Loss of heterozygosity from all the abnormal cells in a lesion indicates monoconal proliferation and is a molecular marker of neoplasia.

heterozygosity

the state of having different alleles in regard to a given character.
References in periodicals archive ?
All but SSW appear to be genetically robust in terms of expected levels of heterozygosity and low levels of genetic differentiation among subpopulations, indicating that this species is an efficient outcrosser.
Diversity estimates obtained with allozymes indicate that these populations have lower allelic diversity and low level of observed heterozygosity.
Nonetheless, estimates of observed and expected heterozygosity, as well as [F.
Using microarrays to search for tumour gene copy number changes and loss of heterozygosity actually started a few years ago.
For gray snappers, the number of alleles per microsatellite ranged from two (Lca 43 and Lca 91) to 15 (Ra 6), and expected and observed heterozygosity per microsat ellite ranged from 0.
Loss of heterozygosity occurs when all or part of a chromosome is lost during the development of cancer.
A critical determinant of heterozygosity is the amount of gene flow between spatially segregated demes (Hansson et al.
Although correlations between the degree of individual heterozygosity and fitness-related characters have been commonly described in natural populations of many species, the genetic basis of these associations remains poorly understood (see reviews by Mitton and Grant 1984; Zouros and Foltz 1987; Houle 1989; Zouros and Pogson 1994; Hedgecock et al.
Finally, we have an array that has optimal copy number detection, including the potential for exon-by-exon coverage, that also has SNPs to detect absence of heterozygosity [AOH] caused by UPD or consanguinity," said Dr.
SNP arrays are also capable of detecting loss of heterozygosity and haplotype analysis i.