heterotopic ossification


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heterotopic ossification

[-top′ik]
Etymology: Gk, heteros + topos, place
a nonmalignant overgrowth of bone, frequently occurring after a fracture, that is sometimes confused with certain bone tumors when visualized on x-ray film. Also called exuberant callus, myositis ossificans.

myositis ossificans

A term that is slowly being retired from the medical literature, largely in favour of heterotopic ossification, given that
(1) inflammation is not a necessary precursor for heterotopic ossification; and
(2) the ossification doesn’t always occur in muscle, but may occur in fascia, tendons, and other mesenchymal soft tissues.

Clinical forms, myositis ossificans
• Localised: linked to trauma.
• Generalised: now known as fibrodysplasia ossificans progressiva, which is often due to spontaneous mutation, resulting in autosomal dominant pattern of inheritance in the proband’s progeny.

het·er·o·top·ic os·si·fi·ca·tion

(het'ĕr-ō-top'ik os'i-fi-kā'shŭn)
Growth of calcium deposits within soft tissue, usually at the site of a hematoma due to blunt trauma or in tissue atrophied due to central nervous system injury.
Synonym(s): myositis ossificans.

heterotopic ossification

The development of mature lamellar bone in soft tissue that does not normally contain bone. The condition is usually associated with trauma in or around a joint or following severe head or spinal cord injuries. Heterotopic ossification is also found in the rare autosomal dominant condition of MYOSITIS OSSIFICANS.
References in periodicals archive ?
5% rate of heterotopic ossification in all total hip arthroplasties performed in that institution.
They postulated that in most heterotopic ossifications three factors are needed for the process to occur: an inciting event, usually represented by a trauma, a signal from the site of the injury, most likely represented by bone morphogenetic proteins secreted by the tissue cells, and an appropriate environment allowing the induction of newly formed bone.
The results of surgical treatment for posttraumatic heterotopic ossification and ankylosis of the elbow.
Bellemans, "Ankylosis due to heterotopic ossification following primary total knee arthroplasty," Acta Orthopaedica Belgica, vol.
Risk factors for heterotopic ossification in patients with spinal cord injury: A case-control study of 264 patients.
Prostaglandin E2 measurements: Their value in the early diagnosis of heterotopic ossification in spinal cord patients.
They took into account variables like age and gender of the patient, location and mechanism of injury, location of the heterotopic ossification, presence and severity of brain injury.
Prophylactic antibiotics were administered for 24 hours, and heterotopic ossification prophylaxis was not used.
Thirteen months after the operation, heterotopic ossification was present, but there was no local recurrence of the osseous projection, and no complications such as dislocation or infection had occurred.
2) It presents clinically with characteristic short great toes and heterotopic ossification involving multiple sites.
Heterotopic ossification (HO) is extra bone growth often caused by serious injuries from explosions.