heterotopic ossification

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heterotopic ossification

Etymology: Gk, heteros + topos, place
a nonmalignant overgrowth of bone, frequently occurring after a fracture, that is sometimes confused with certain bone tumors when visualized on x-ray film. Also called exuberant callus, myositis ossificans.

myositis ossificans

A term that is slowly being retired from the medical literature, largely in favour of heterotopic ossification, given that
(1) inflammation is not a necessary precursor for heterotopic ossification; and
(2) the ossification doesn’t always occur in muscle, but may occur in fascia, tendons, and other mesenchymal soft tissues.

Clinical forms, myositis ossificans
• Localised: linked to trauma.
• Generalised: now known as fibrodysplasia ossificans progressiva, which is often due to spontaneous mutation, resulting in autosomal dominant pattern of inheritance in the proband’s progeny.

het·er·o·top·ic os·si·fi·ca·tion

(het'ĕr-ō-top'ik os'i-fi-kā'shŭn)
Growth of calcium deposits within soft tissue, usually at the site of a hematoma due to blunt trauma or in tissue atrophied due to central nervous system injury.
Synonym(s): myositis ossificans.

heterotopic ossification

The development of mature lamellar bone in soft tissue that does not normally contain bone. The condition is usually associated with trauma in or around a joint or following severe head or spinal cord injuries. Heterotopic ossification is also found in the rare autosomal dominant condition of MYOSITIS OSSIFICANS.
References in periodicals archive ?
Abbreviations: BMP = bone morphogenetic protein, BV = bone volume, CNS = central nervous system, microCT = microcomputed tomography, H&E = hematoxylin and eosin, HO = heterotopic ossification, RNA = ribonucleic acid, RTPCR = reverse transcript polymerase chain reaction, SCI = spinal cord injury, T = thoracic, VA = Department of Veterans Affairs.
A few heterotopic ossification cases developing after abdominal surgery have been reported in the literature (6, 7).
Heterotopic ossification (HO), a process where true bone forms outside the bone within muscle tissue (Banovac and Banovac 2002, Lal et al 1989) is a common complication following SCI, occurring below the level of the lesion in the paralyzed limbs (Banovac and Gonzalez 1997) .
Symptomatic heterotopic ossification after very severe traumatic brain injury in 114 patients: Incidence and risk factors.
Prostaglandin E2 measurements: Their value in the early diagnosis of heterotopic ossification in spinal cord patients.
This process, known as heterotopic ossification (HO), occurs in muscles, tendons and ligaments, and causes significant morbidities and progressive disability.
We present a case of heterotopic ossification of the penis with associated erectile dysfunction in a 46-year-old male who sustained an anteroposterior compression type II (APC II) pelvic ring disruption in the absence of any associated GU injury.
The classical definition of heterotopic ossification (HO), set forth by Hsu and Keenan [1], focuses on the formation of lamellar bone in periarticular, nonossified soft tissues [1-2].
The purposes of this study were to report our experiences with high-energy wartime extremity wounds, to define the prevalence of heterotopic ossification in these patients, and to determine the factors that might lead to development of the condition," said lead author Lieutenant Commander Jonathan Agner Forsberg, MD.
0%) developed heterotopic ossification as demonstrated radiographically.