heterophile


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Related to heterophile: heterophile antigen

heterophil

 [het´er-o-fil″]
1. a finely granular polymorphonuclear leukocyte represented by neutrophils in human, but characterized in other mammals by granules that have variable sizes and staining characteristics.
2. heterophilic (def. 1).
heterophil antibody a characteristic antibody found with infectious mononucleosis, demonstrated in 90 to 95 per cent of adolescents and adults and 50 per cent of children with the disease. It declines in titer after acute illness has resolved but may be detectable for up to 9 months after disease onset.

het·er·o·phil

, heterophile (het'ĕr-ō-fil, -fīl),
1. Pertaining to heterogenetic or cross-reacting antigens occurring in different species or to antibodies directed against such antigens.
2. The neutrophilic leukocyte in humans; in some animals, the granules vary in size and staining reaction.
[hetero- + G. philos, fond]

heterophile

het·er·o·phil

, heterophile (het'ĕr-ō-fil, -fīl)
1. The neutrophilic leukocyte.
2. Pertaining to heterogenetic antigens occurring in different species or to antibodies directed against such antigens.
[hetero- + G. philos, fond]
References in periodicals archive ?
The possibility of heterophile antibody interference was investigated with an HBT.
You don't need a heterophile [antibody test], you don't ever want to follow up if that test ever becomes negative, and you don't need specific serology.
EBV primary infection is traditionally detected through a positive heterophile antibody test.
Evaluation for heterophile-blocking antibodies with the Scantibodies Heterophilic Blocking Tube in serum did not alter the TSH results, suggesting the absence of heterophile antibody interference.
Heterophile antibodies, specific auto-antibodies or rheumatoid factor can interfere in numerous immunoassays, by binding to reagent antibodies or particles, causing falsely increased or decreased results (Fig.
22) Heterophile (monospot) testing is a practical clinical option for EBV infection.
Submission of dietary semi-refined oil with vitamin E didn't have any significant effect on heterophile, lymphocyte count and H/L ratio in layers.
He ultimately was discharged with a diagnosis of mononucleosis because of a positive heterophile test.
The new product detects the heterophile antibody produced during infection by the Epstein-Barr virus which causes infectious mononucleosis.
The current rapid methods for the diagnosis of infectious mononucleosis rely primarily on the patient's symptoms and non-specific heterophile antibody testing.
Publications regarding the lack of analytical specificity owing to confounders, such as heterophile antibodies and rheumatoid factor, date back to the early 2000s after the initial introduction of cardiac troponin assays.
2,3) Other interferences fall into the category of species-nonspecific heterophile antibodies.