heterophile antibodies

(redirected from heterophil antibodies)

heterophile antibodies

human antibodies capable of binding to animal immunoglobulins and possibly of interfering with reaction of animal-derived antibodies and analyte, which comprise all immunoassays. The three groups of heterophile antibodies are polyspecific antibodies, antiimmunoglobulin antibodies, and high-specificity high-affinity antibodies against antigens from animal species. In clinical practice, the most important significance of heterophile antibodies is their use in diagnosing infectious mononucleosis.
References in periodicals archive ?
Lab tests, such as complete blood counts, heterophil antibodies, and Epstein-Barr titers, may show abnormalities characteristic of the disease but are not reliable for making decisions about sports readiness.
12] Since 5% to 10% of patients with IM test negative for heterophil antibodies, [1] students who had met the clinical and hematological criteria and who had demonstrated a fourfold rise in titer of EBV capsid antigen antibodies were also included in the IM group.