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hereditary nonpolyposis colon cancer |
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hereditary nonpolyposis colon cancer Lynch I syndrome Oncology A relatively distinct AD form of cancer that may account for 5-10% of all colorectal CA Clinical Family Hx of colorectal CA at relatively young age, primarily of proximal colon,
tendency toward multiple primary tumors; HNPCC may be ssociated with extracolonic tumors–eg, of endometrium Diagnosis Amsterdam criteria. See Amsterdam criteria, Colorectal cancerhMSH-2. Cf Familial adenomatous polyposis. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| Hereditary nonpolyposis colon cancer (HNPCC) syndrome is a genetic condition characterized by early-onset colorectal cancer (i. Fishel R, Lescoe MK, Rao MR, et al: The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer. Though three of her five sisters developed colon cancer, they chose not to be tested for the gene, known officially as hereditary nonpolyposis colon cancer or |
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