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Hepatotoxin

   Also found in: Dictionary/thesaurus, Wikipedia 0.03 sec.
hepatotoxin /hep·a·to·tox·in/ (hep´ah-to-tok″sin) a toxin that destroys liver cells.hep´atotoxic
hep·a·to·tox·in (hp-t-tksn, h-pt-)
n.
A toxin that is destructive to liver parenchyma.
Hepatotoxin
A substance that is toxic to the liver.
Mentioned in: Hepatitis, Drug-Induced
hepatotoxin
a toxin that destroys liver cells.
fungal hepatotoxin
includes some of the most potent hepatotoxins, e.g. sporidesmin, aflatoxin, rubratoxin, and the toxin of Phomopsis leptostromiformis, a fungus growing on lupins.


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For example, gene expression profiling has been used to classify hepatotoxins based on mechanism of action and to differentiate early, presumably adaptive, responses from later responses that are reflective of toxicity (Hamadeh et al.
Meeting report: Validation of Toxicogenomics-Based Test Systems: ... by Schechtman, Leonard M. / Environmental Health Perspectives
Cyanobacterial hepatotoxins can kill an animal within 24 hours, says Michele A.
Ancient Whodunit: scientists indict wee suspects in ancient deaths. ... by Perkins, S. / Science News
VIVITROL does not appear to be a hepatotoxin at the recommended doses.
Alkermes and Cephalon Issue Statement in Response to COMBINE Study ... by Business Wire
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