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hepatorenal syndrome

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hepatorenal syndrome
n.
A condition in which acute renal failure occurs with disease of the liver or biliary tract, the cause of which is believed to be either a decrease in renal blood flow or damage to both the liver and the kidneys as from carbon tetrachloride poisoning or leptospirosis. Also called hepatonephric syndrome.

hepatorenal syndrome,
a type of kidney failure characterized by a gradual loss of function without signs of tissue damage. It is associated with hepatitis or cirrhosis of the liver; its exact cause is unknown.

hepatorenal syndrome
Bile nephrosis Hepatology A complication of liver failure characterized by acute renal dysfunction without renal pathology, due to ↓ perfusion, hypovolemia, and hyperaldosteronism, 2º to liver disease–eg, cirrhosis, acute fatty liver, hepatic failure, obstructive jaundice, sepsis, infectious hepatitis Etiology Unclear Clinical ↓/absent urine, jaundice, bloating, delirium, confusion, N&V Prognosis Very poor;13 relentlessly deteriorate. Cf Cirrhotic glomerulonephritis.


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Improvement in renal function in hepatorenal syndrome with N-acetylcysteine.
 
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